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Cytochrome P450 alleles, Asians, and Omeprazole

55% of Asian patients versus 30% Caucasian patients are missing the allele for the CYT450 system needed for omeprazole metabolism. Thus, Asian patients may experience more complications from omeprazole use after percutanous coronary intervention. “Dual anti-platelet therapy (DAPT) with Aspirin and a Thienopyridine-derivative P2Y12 Inhibitor (commonly Clopidogrel) is mandatory after Percutaneous Coronary Intervention (PCI). H2 receptor antagonists (H2RA) or Proton ... Read More »

Increased Occult Atrial Fibrillation in Cryptogenic Stroke Asian Patients

71 patients with cryptogenic stroke had implantable loop monitor placement. Primary endpoint of atrial fibrillation detection was via implantable loop monitor: incidence at 6 months was 12.9%; at 12 months of 15.2%. The authors concluded that occult atrial fibrillation is high in Asian patients with cryptogenic stroke. http://doi/10.1016/j.jstrokecerebrovasdis.2018.03.019.  accessed 18 September 2018. Contributors: Gloria Wu MD, Kevin Lu BS Read More »

New genes found to be associated with atrial fibrillation in Japanese population

In 2017, Japanese researchers discovered six new genes associated with atrial fibrillation in Japanese individuals: study involved 8180 patients with atrial fibrillation and 28612 control patients. The genetic loci identified include KCND3, HAND2, NEBL, PPFIA4, SLC1A4-CEP68, and SH3PXD2A for atrial fibrillation. Low S, Takahashi A, Ebana Y et al. Identification of six new genetic loci associated with atrial fibrillation in the Japanese population Nature Genetics 49, 953-958 ... Read More »

long flights to Asia and UV exposure to pilots

Exposure to uv radiation increases approximately 5% for every 1000 feet of altitude. Both infrared (IR) and ultraviolet (uv) radiation are present in our environment, depending on the time of day, year, latitude, altitude and weather conditions and reflectivity of the surrounding surfaces, the pilot will receive more or less radiation. uv-a (400 – 315 nm), uv-B (315 – 280 ... Read More »

photoreceptor ganglion cells and vision

New research shows that in our retina, we have “photoreceptor ganglion cell” which responds to light at 480 nanometer wavelength. This wavelength causes abnormal sleep cycle. But this same cell allows previous blind people to SEE!   In the latest research, they took people born with abnormal eyes and thought to be blind and found they could see when exposed ... Read More »

Vitamin D and cognitive function?

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Vitamin D is a fat soluble vitamin. Main sources of Vitamin D come from the skin as well as our diet. Vitamin D is mostly commonly known for its importance in bones and now it has been shown to be important for cognitive function. A recent study has found that low levels of vitamin D may be linked to losing ... Read More »

Coconut Oil? Good or Bad

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There are claims that coconut oil, a saturated fatty acid, can help with high cholesterol. However, the American Heart Association and United States Department of Agriculture feel that we have to be careful! Read More »

17 Red Flag Signs of Cancer

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According to a new report from the Cancer Research UK, 1 in 2 people will develop cancer over the course of their lives because of the aging population. Signs of cancer for men and women: An unusual lump or swelling anywhere on your body A change in the size, shape or colour of a mole A sore that won’t heal ... Read More »