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Artificial Intelligence to Help Physicians Diagnose

A recent article in the New York Times (Feb 11, 2019)1 reports that artificial intelligence (AI) can be used to make a diagnosis in a pediatric population of 600,000 patients. The data involved 101.6 million data points derived from 1,362,559 patient visits from a pediatric hospital in Guangzhou China.2 Machine learning in this study associated common medical disorders with patient ... Read More »

Philippines Department of Health Confirms Measles Outbreak

On February 6, 2019, the Philippines Department of Health declared a measles outbreak in Manila, Philippines with over 400 cases and five confirmed deaths from January 1, 2019.  One day later, health officials declared that the outbreak spread to other surrounding regions. As of February 11, 2019, the number of measles cases in the Philippines has risen to 4,300 people ... Read More »

Singaporean Chinese Women: Abdominal obesity is worse for cardiovascular health than general obesity

The incidence of obesity has been steadily rising in developed and developing countries, affecting 13% of the global adult population. Obesity is strongly associated with health complications and diseases such as diabetes, hypertension, and other cardiovascular diseases1. In one recent study conducted by Goh and Hart with 1,326 Singaporean Chinese women aged 29 to 71, the researchers found that only ... Read More »

Han Chinese: Gene polymorphisms associated with risk of age-related macular degeneration

Age-related macular degeneration (AMD) is a leading cause of blindness in patients greater than 55 years of age in the US. Age-related macular degeneration  affects 2.44% of Chinese people aged 45-49 years; 18.98% of Chinese people aged 85-89 years³.  Researchers from the Department of Ophthalmology of Huazhong University of Science and Technology, China concluded that four gene polymorphisms, CX3CR1 839C/T ... Read More »

East Asians and the ALDH2*2 gene

The gene ALDH2, encodes the aldehyde dehydrogenase enzymes which serve to break down  aldehydes after alcohol consumption. However, 540 million people globally of the East Asian descent carry the ALDH2*2 gene variant which is the inactive form of the ALDH2 gene¹. This leads to the accumulation of aldehydes which can result in an increased risk of several types of cancer ... Read More »

Major differences in cardiovascular risk profiles in Chinese Australians as compared to non-Chinese

Chinese Australians have lower cardiovascular disease and stroke incidence as compared with non-Chinese Australians. However, they have worse cardiovascular risk profiles, including a higher prevalence of diabetes, smoking, and a lower exercise level. Furthermore, mixed-Chinese populations have even worse cardiovascular risk profiles. 1. Marked differences in cardiovascular risk profiles in middle-aged and older Chinese residents: Evidence from a large Australian ... Read More »

The Ministerial Conference on Diabetes 2018

The diabetes epidemic is a serious global health issue. In 2016, there were 422 million people worldwide with diabetes (8.5% of the world population), and 1.2 million reported deaths directly caused by diabetes1. As part of a global effort to combat this epidemic, Singapore is hosting the 2018 Ministerial Conference on Diabetes from November 26-27, where over 300 international and ... Read More »

Zika Virus Outbreak in India 2018

India is facing its largest Zika virus outbreak with over 100 cases in Rajasthan, India, including several pregnant women with its first confirmed case in September 20181.  Zika virus is a mosquito-borne disease primarily prevalent in tropical areas around the world such as Brazil, Mexico, and India.  People infected with this virus experience mild or no symptoms at all. Symptoms ... Read More »

Asian Americans are more likely to get gastric cancer

Gastric cancer has a low incidence in the United States, affecting 8.1 males and females of all races per 100,000 based on SEER data from 20001. However, many Asian American ethnic groups have elevated incidence of gastric cancer that are overlooked and should merit additional screening. For example, in one study conducted by Miller et al. in 2008 found that ... Read More »

Cytochrome P450 alleles, Asians, and Omeprazole

55% of Asian patients versus 30% Caucasian patients are missing the allele for the CYT450 system needed for omeprazole metabolism. Thus, Asian patients may experience more complications from omeprazole use after percutanous coronary intervention. “Dual anti-platelet therapy (DAPT) with Aspirin and a Thienopyridine-derivative P2Y12 Inhibitor (commonly Clopidogrel) is mandatory after Percutaneous Coronary Intervention (PCI). H2 receptor antagonists (H2RA) or Proton ... Read More »