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Author Archives: Gloria Wu

Cytochrome P450 alleles, Asians, and Omeprazole

55% of Asian patients versus 30% Caucasian patients are missing the allele for the CYT450 system needed for omeprazole metabolism. Thus, Asian patients may experience more complications from omeprazole use after percutanous coronary intervention. “Dual anti-platelet therapy (DAPT) with Aspirin and a Thienopyridine-derivative P2Y12 Inhibitor (commonly Clopidogrel) is mandatory after Percutaneous Coronary Intervention (PCI). H2 receptor antagonists (H2RA) or Proton ... Read More »

Increased Occult Atrial Fibrillation in Cryptogenic Stroke Asian Patients

71 patients with cryptogenic stroke had implantable loop monitor placement. Primary endpoint of atrial fibrillation detection was via implantable loop monitor: incidence at 6 months was 12.9%; at 12 months of 15.2%. The authors concluded that occult atrial fibrillation is high in Asian patients with cryptogenic stroke. http://doi/10.1016/j.jstrokecerebrovasdis.2018.03.019.  accessed 18 September 2018. Contributors: Gloria Wu MD, Kevin Lu BS Read More »

New genes found to be associated with atrial fibrillation in Japanese population

In 2017, Japanese researchers discovered six new genes associated with atrial fibrillation in Japanese individuals: study involved 8180 patients with atrial fibrillation and 28612 control patients. The genetic loci identified include KCND3, HAND2, NEBL, PPFIA4, SLC1A4-CEP68, and SH3PXD2A for atrial fibrillation. Low S, Takahashi A, Ebana Y et al. Identification of six new genetic loci associated with atrial fibrillation in the Japanese population Nature Genetics 49, 953-958 ... Read More »

What to eat for diabetes

Diabetics need to limit carbohydrates to control their diabetes. For example, rice is a staple in many cultures. We suggest substitutes such as quinoa which has higher protein content than other carbohydrates. We suggest using raw lettuce as a “wrap” for sandwich meat or other sources of protein. We recommend using a smaller dinner plate or dessert plate so that food ... Read More »

European Society of Cardiologists Meeting NEWS

Fewer carbohydrates and more fat reduce mortality: Data from 135,000 patients across 5 continents suggest that fewer carbs may reduce death non-Cardiovascular mortality. It was found that total fat intake in the highest vs lowest quartile was associated with a significant 23% reduction of total mortality risk, and 18% reduced risk of stroke and a 30% reduced risk of non-cardiovascular ... Read More »

New California law AB 1726 will disaggregate data for Asian Americans

New Calif law AB 1726 will disaggregate data for Asian Americans.  The new categories include Bangladeshi, Hmong, Indonesian, Malaysian, Pakistani, Sri Lankan, Taiwanese, Thai, Fijian, and Tongan Americans. Roughly 15 percent of California’s population is Asian and 0.5 percent Native Hawaiian or other Pacific Islander.  This was signed into law in September 2016. Advancing Justice’s analysis of Census data found that ... Read More »

Aspartame can lead to blindness

1987 Aspartame contains methanol and excessive consumption can lead to retrobulbar neuritis. See article: http://www.janethull.com/healthynews/blog/2014/06/in-the-blink-of-an-eye-how-aspartame-can-harm-your-vision/ Read More »

long flights to Asia and UV exposure to pilots

Exposure to uv radiation increases approximately 5% for every 1000 feet of altitude. Both infrared (IR) and ultraviolet (uv) radiation are present in our environment, depending on the time of day, year, latitude, altitude and weather conditions and reflectivity of the surrounding surfaces, the pilot will receive more or less radiation. uv-a (400 – 315 nm), uv-B (315 – 280 ... Read More »

photoreceptor ganglion cells and vision

New research shows that in our retina, we have “photoreceptor ganglion cell” which responds to light at 480 nanometer wavelength. This wavelength causes abnormal sleep cycle. But this same cell allows previous blind people to SEE!   In the latest research, they took people born with abnormal eyes and thought to be blind and found they could see when exposed ... Read More »